Abstract: The use of aqueous decoction of Leonotis leonurus in the treatment of hypertension in traditional medicine is well documented.

Abstract: Crimum macowanii has been used extensively in traditional medicines for treatment of various illnesses such as oedema and heart disease.

Abstract: The present day study was conducted to determine if the L. leonurus effect on isolated rat heart is due to ionic changes in the perfusion fluid.

Abstract: Pyrazinamide, a drug used in the regimen for the treatment of drug-sensitive tuberculosis, is also used for the treatment of multidrug-resistant tuberculosis (MDR-TB).

Abstract: The aim of the study was to describe the PK and simulate doses to assess PD attainment.

Abstract: Studies conducted in primates and some observational human data have raised concern regarding the association of first-trimester EFV- exposure with central nervous system congenital abnormalities.

Abstract: Plants used in traditional medicine have served as sources of some of the drug compounds used in medicine today, and could still serve as leads for the development of new drugs to treat existing conditions.

Abstract: To find out if HIV- infection affects the time to sputum culture conversion during the treatment of drug- resistant (DR) tuberculosis (TB).

Abstract: Ethionamide (ETH) is active against Mycobacterium tuberculosis (MTB) with a median minimum inhibitory concentration (MIC) of 0.5 µg/mL.

Abstract: The National Health Laboratory Services (NHLS) uses the phenotypic drug susceptibility test and the line probe assay for isoniazid (INH) and rifampicin (RIF), a qualitative drug sensitivity test (DST) method, to determine anti-tuberculosis drugs DST. Mycobacterium tuberculosis (MTB) is heterogeneous.